Total Shoulder Replacement. Total shoulder replacement is a complex procedure that involves replacing the shoulder joint with artificial parts. Our shoulder specialists have performed numerous shoulder replacements at Johns Hopkins and appreciate an opportunity to share their knowledge. They have provided answers to some of the most frequently asked questions about the total shoulder replacement procedure.Total Shoulder Replacement What is a total shoulder replacement? During shoulder replacement surgery, the damaged parts of the shoulder are removed and replaced with artificial components, called a prosthesis. The treatment options are either replacement of just the head of the humerus bone (ball), or replacement of both the ball and the socket (glenoid).